LCMS (electrospray and APPI)

Our dedicated Shimadzu LCMS-2010 EV system is available for analysis of both single compounds and complex mixtures.
A highly sensitive detector allows for samples as small as 10 pg to be analysed and detected.

Our LCMS services include:

  • Electrospray ionisation (ESI) and atmospheric pressure chemical ionisation (APCI) probes for a range of analytes, from non-polar to highly polar compounds.
  • m/z range of 10 – 2000 amu (ESI having a wider range than APCI).
  • Development of both generic and compound specific methodologies.
  • Impurity profiling – attachment of analytical HPLC columns with the use of a splitter feed to increase the resolution between compounds and allow the determination of molecular weights.
  • Structure determination of unknowns.