NewChem Technologies has an experienced team of chemists with considerable expertise in the synthesis of glucuronide metabolites.
A glucuronide is a glycoside type compound. It is any substance produced by linking via a glycosidic bond a glucuronic acid to another molecule which is not a saccharide. Generally inactive, glucuronides constitute the major proportion of the metabolites of many alcohols, phenols and carboxylic acids.
The conversion of chemical compounds to glucuronides is called glucuronidation. It is a method used by animals to assist in the excretion of substances that cannot be used as an energy source such as medicines, drugs and others toxic substances.
The glucuronide metabolite created is more soluble in water than the original substance and is more easily excreted by the kidneys.
Established examples are buprenorphine glucuronide, paracetamol glucuronide and morphine-6-glucuronide
NewChem Technologies offers a bespoke contract chemical service for the synthesis and analysis of glucuronide metabolites. We are usually able to offer fixed price quotations but when needed, competitive FTE based contracts can be arranged.
Our goal is to meet your requirements and so we attach great importance to delivering results and meeting deadlines. Strict confidentiality is also an integral feature of all our contract services.
Please feel free to detail your glucuronide metabolite needs so that we can respond to your request as soon as possible.